Transformational cell therapies for patients with serious diseases.

Mike Hughes

Michael G. Hughes, Jr., MD

Chief Medical Officer (Koligo Therapeutics Inc.)

Mike Hughes is a transplant surgeon that started the clinical islet transplant program at Jewish Hospital and has personally performed over 50 total pancreatectomies with islet auto transplantation in Louisville. He has been invited to present on islet auto-transplantation at the National Institutes of Health, the American Transplant Congress, Center for Medicare and Medicaid Services, and other academic institutions. He applied for and was awared National Pancreas Foundation Center status for Chronic Pancreatitis on behalf of Jewish Hospital. He was previously the Director of the Pancreatic Disease Center at Jewish Hospital and Director of Pancreas and Islet Transplantation at the University of Louisville. Mike is the Director of Vanguard Surgical LLC in Louisville.

Mike created the clinical program infrastructure from scratch, beginning with only a part time medical assistant and no support from the transplant program. He established all the reimbursement strategies and clinical evaluation protocols, recruited all multidisciplinary team members, scheduled and performed all the surgeries, and arranged for all patient follow-up. It was only after securing funding and achieving outcomes that exceeded benchmarks for the first 9 cases did the transplant program begin providing support. After achieving an average contribution margin for the hospital of approximately $65,000 per case, Jewish Hospital created the Pancreatic Disease Center and named him Director.

Mike completed his undergraduate (B.A. in English Literature) and medical education (M.D.) at Wake Forest University. He then trained in General Surgery at the University of Virginia and Transplant Surgery at the University of Minnesota. Under Dr. David Sutherland, he learned how to perform total pancreatectomy with islet auto transplantation. As an Assistant Professor of Surgery at the Medical University of South Carolina, he helped with the initiation of their islet auto transplant program. He then joined the University of Louisville, as a professor and surgeon in the Department of Surgery and Director of Pancreas and Islet Transplantation. Mike subsequently created and operates Vanguard Surgical, LLC in Louisville.

Outside of the office, he enjoys spending time with family, travel, reading, hiking, and music. When he can get back home to Annapolis, MD, he enjoys spending time on and around the Chesapeake Bay.

Koligo personalized cell therapy for chronic pancreatitis. Because pain should not define your life.