Transformational cell therapies for patients with serious diseases.

Koligo is dedicated to advancing R&D and technologies to cure pancreatic disease.

The people, science and innovative mindset
to forever improve the lives of people we touch.


Matthew Lehman,

Chief Executive Officer (Koligo Therapeutics Inc.) and Executive Director

  • Proven biotech & cell therapy executive
  • NASDAQ-listed Prima Biomed, CSE-listed M Pharmaceutical, private CRO SPRI Clinical Trials
  • Clinical research & manufacturing scale-up expertise
  • MS Columbia; BA Louisville

Balamurugan N. Appakalai, PhD,

Chief of Manufacturing (Koligo Therapeutics Inc.)

  • 20+ years experience in islet cell isolation; 800 human & 600 pig pancreases
  • 100+ peer reviewed articles & presentations
  • Previous islet processing at Universities of Minnesota, Colorado in Denver, Pittsburgh

Mike Hughes, MD,

Chief Medical Officer (Koligo Therapeutics Inc.) 

  • Director, Vanguard Surgical in Louisville
  • Initiated TP-IAT program in Louisville
  • 50+ clinical TP-IAT performed to date & negotiated reimbursement
  • MD Wake Forest, residency at Virginia Medical Center, fellowship at University of Minnesota

Stuart Williams, PhD,

Chief Technology Officer (Koligo Therapeutics Inc.) and Executive Director

      • 300+ publications in the field Regenerative Medicine
      • 26 issued US patents in cell & tissue engineering
      • Experienced academic-industry partner: founded three biotech companies
      • PhD cell biology University of Delaware, postdoc Yale School of Medicine