Transformational cell therapies for patients with pancreatic disease

Koligo is dedicated to advancing R&D and technologies to cure pancreatic disease.

The people, science and innovative mindset
to forever improve the lives of people we touch.


Matthew Lehman,

Chief Technology Officer (Koligo Therapeutics Inc.) and Executive Director

  • Proven biotech & cell therapy executive
  • NASDAQ-listed Prima Biomed, CSE-listed M Pharmaceutical, private CRO SPRI Clinical Trials
  • Clinical research & manufacturing scale-up expertise
  • MS Columbia; BA Louisville

Balamurugan N. Appakalai, PhD,

Chief of Manufacturing (Koligo Therapeutics Inc.)

  • 20+ years experience in islet cell isolation; 800 human & 600 pig pancreases
  • 100+ peer reviewed articles & presentations
  • Director of Islet Cell Lab at Cardiovascular Innovation Institute, Louisville
  • Previous islet processing at Universities of Minnesota, Colorado in Denver, Pittsburgh

Mike Hughes, MD,

Chief Medical Officer (Koligo Therapeutics Inc.) 

  • Director of Pancreas Transplantation, Assistant Professor of Surgery, Louisville
  • Initiated TP-IAT program in Louisville
  • 20 clinical TP-IAT performed to date & negotiated reimbursement
  • MD Wake Forest, residency at Virginia Medical Center, fellowship at University of Minnesota

Stuart Williams, PhD,

Chief Technology Officer (Koligo Therapeutics Inc.) and Executive Director

      • Division chief, Bioficial Heart, Cardiovascular Innovation Institude
      • 300+ publications & 16 issued US patents in cell & tissue engineering
      • Experienced academic-industry partner: founded three biotech companies
      • PhD cell biology University of Delaware, postdoc Yale School of Medicine

David Blanford,

Chief Operating Officer (Koligo Therapeutics Inc.)

  • Experienced financial executive for manufacturing and clinical companies
  • Managed private-equity investment, government grants, venture capital investment
  • BS Oral Roberts

Ariel Sivikofsky,

Chief Financial Officer

  • Chartered Accountant (FCA) and graduate member of the Australian Institute of Company Directors (GAICD)
  • Experienced biotech executive for private and public entities in both Australia and Europe
  • BC University of Wollongong

Kyslecel personalized cell therapy for chronic pancreatitis. Because pain should not define your life.